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蘿卜硫素

分析標(biāo)準(zhǔn)品,HPLC≥95%

Sulforaphane

CAS號(hào)：4478-93-7

分子式：C6H11NOS2

分子量：177.29

MDL：MFCD00198068

產(chǎn)品介紹

Sulforaphane 是存在于多種蔬菜中的天然異硫氰酸酯。Sulforaphane 增加腫瘤抑制蛋白的轉(zhuǎn)錄并抑制組蛋白脫乙酰酶的活性。Sulforaphan 可以激活 Nrf2 ，并通過(guò) AMPK 依賴性信號(hào)傳導(dǎo)抑制高糖誘導(dǎo)的胰腺癌。 Sulforaphan 具有抗癌和抗炎活性。

外觀：油狀液體

溶解性：DMSO  :  ≥  62.5  mg/mL  (352.53  mM)

H2O  :  50  mg/mL  (282.02  mM;  Need  ultrasonic)

儲(chǔ)存條件：-20℃，充氮保存

注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

參考文獻(xiàn)(17篇)

17. [IF=4.7] Ziyi Ren et al."Mechanism of sulforaphane in treatment of pancreatic cancer cell based on network pharmacology and in vitro experiments."BIOORGANIC CHEMISTRY.2025 Jul;:108754

16. [IF=6.2] Jiali Wang et al."Inhibition of Glucosinolate Sulfatases to Combat Plutella xylostella: Development of Novel Phenylcarboxamide Derivatives for Plant-Integrated Pest Management."JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY.2025;XXXX(XXX):XXX-XXX

15. [IF=6.2] Shuang Li et al."Sulforaphane Promotes the Skeletal Muscle Postinjury Regeneration by Up-Regulating the Transcription of Prl2c2 through JAK2/STAT3 Signaling."JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY.2025;XXXX(XXX):XXX-XXX

14. [IF=5.7] Xili Liang et al."Characterization of Myrosinase-Mediated Glucosinolate Degradation Pathways in Lactiplantibacillus plantarum ZUST49."JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY.2025;XXXX(XXX):XXX-XXX

13. [IF=5.7] Jiaqi Wang et al."Mining of Novel Myrosinase with High Activity Based on Sequence and Structure Clustering for Efficient Preparation of Sulforaphane."JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY.2025;73(13):7954–7965

12. [IF=3.1] Yu-Hong Zhang et al."Insight into the Sulforaphane Content and Glucosinolate Profile of Broccoli Stems After Heat Treatment."Horticulturae.2025 Apr;11(4):383

11. [IF=4.4] Ren Li et al."Encapsulation of Sulforaphane from Cruciferous Vegetables in mPEG-PLGA Nanoparticles Enhances Cadmium’s Inhibitory Effect on HepG2 Cells."Nanomaterials.2025 Jan;15(8):615

10. [IF=2.6] Shi Xiaotong et al."Exogenous addition of EGTA alters Ca2+ and Fe2+ content in broccoli hairy roots and affects sulforaphane production: based on transcriptomic analysis."IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-PLANT".2024 May;:1-22

9. [IF=6.443] Lili Wang et al."High-level and reusable preparation of sulforaphane by yeast cells expressing myrosinase."Food Chemistry-X.2023 Jun;18:100668

8. [IF=6.317] Shaotong Ma et al."The protective effects of sulforaphane on high-fat diet-induced metabolic associated fatty liver disease in mice via mediating the FXR/LXRα pathway."Food & Function.2022 Nov;:

7. [IF=6.117] Jinjin Pan et al."Sulforaphane alleviated vascular remodeling in hypoxic pulmonary hypertension via inhibiting inflammation and oxidative stress."JOURNAL OF NUTRITIONAL BIOCHEMISTRY.2022 Oct;:109182

6. [IF=5.811]

5. [IF=5.279] Lili Wang et al."Biochemical Characterization of a Novel Myrosinase Rmyr from Rahnella inusitata for High-Level Preparation of Sulforaphene and Sulforaphane."J Agr Food Chem. 2022;XXXX(XXX):XXX-XXX

4. [IF=5.279] Shuhua Tian et al."Sulforaphane Regulates Glucose and Lipid Metabolisms in Obese Mice by Restraining JNK and Activating Insulin and FGF21 Signal Pathways."J Agr Food Chem. 2021;XXXX(XXX):XXX-XXX

3. [IF=1.871] Yazhong  Ge et al."Su Yang Decoction induces human colon carcinoma cell apoptosis by activating caspases."Oncol Lett. 2019 Jan;17(1):422-431

2.  張錦華, 郭楠, 楊妍,等. 西蘭花副產(chǎn)物中蘿卜硫素提取、純化及鑒定[J]. 食品科學(xué), 2019, 40(08):256-263.

1.  譚靜,易國(guó)棟.蘿卜硫素介導(dǎo)HDAC6信號(hào)通路改善肌紅蛋白誘導(dǎo)的腎小管上皮細(xì)胞凋亡[J].中藥材,2019,42(09):2181-2184.